Unveiling new biological relationships using shared hits of chemical screening assay pairs
نویسندگان
چکیده
منابع مشابه
Unveiling new biological relationships using shared hits of chemical screening assay pairs
MOTIVATION Although the integration and analysis of the activity of small molecules across multiple chemical screens is a common approach to determine the specificity and toxicity of hits, the suitability of these approaches to reveal novel biological information is less explored. Here, we test the hypothesis that assays sharing selective hits are biologically related. RESULTS We annotated th...
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ژورنال
عنوان ژورنال: Bioinformatics
سال: 2014
ISSN: 1460-2059,1367-4803
DOI: 10.1093/bioinformatics/btu468